Exploring the Connection Between the Microbiome and Allergy Development

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This education is about:

  • Effects of gut dysbiosis in infants and children
  • The intersection of the microbiome, allergen sensitization, and food allergy development
  • Diagnosis and management of cow’s milk protein allergy (CMPA)
  • Probiotics as a tool for the management of CMPA
  • Clinical and pharmacoeconomic benefits of Lactobacillus rhamnosus GG (LGG) for CMPA

Why it matters:

The incidence of food allergy is rising, affecting an estimated 220 million children worldwide. In recent years, evidence for the role of gut dysbiosis in food allergy has emerged, and our understanding of the importance of the microbiome in immune tolerance has expanded. Providers should be aware of the latest data supporting these interactions as well as novel clinical interventions that can support oral tolerance acquisition in infants with cow’s milk protein allergy.

Target Audience:

Developed to support primary care physicians, general practitioners, pediatricians, and other healthcare providers who treat infants and children.

Course Credit:

0.75 AMA PRA Category 1 CreditTM


Opens: 2024-05-31
Closes: 2026-05-31

This activity is supported by an educational grant from Mead Johnson Nutrition.
  • Jenifer Lightdale, MD, MPH

    Associate Chief, Division of Gastroenterology, Hepatology and Nutrition
    Boston Children’s Hospital
    Professor of Pediatrics
    Harvard Medical School
    Boston, Massachusetts

Learning Objectives

  • Describe the diagnostic approach for CMPA, including clinical presentation, differential diagnosis, and diagnostic guidelines and criteria
  • Recognize the role of the gut microbiome in immune system development and its subsequent impact on the risk of allergic disease
  • Summarize the clinical and pharmacoeconomic impact of hypoallergenic formulas with probiotic LGG® in the management of CMPA